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Post by amylou on Feb 18, 2005 10:10:52 GMT -5
I have been using Proactiv's Skin Lightnening Lotion..I have put it on several times in one day..and I can already see a difference You can buy it at the mall with the stands of proactiv..i am not sure about online.. yea try it!
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Post by lauryn on Feb 18, 2005 12:43:51 GMT -5
the active ingredient is hydroquinone which is a suspected carcinogen and skin toxicant
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Post by amylou on Feb 18, 2005 15:49:13 GMT -5
what does that mean
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Nelly
Full Member
Posts: 163
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Post by Nelly on Feb 18, 2005 16:41:27 GMT -5
I just did some digging around and could not find any really bad warnings about hydroquinone. It looks like it should be fairly safe to use. Here's a post that I copied from a newsgroup:
> 1. How toxic is hydroquinone?
Not very. It is safe for use on small areas of the skin. It is sold as a cosmetic in strengths up to 2% in Europe.
>2. Does it interact with benzoyl peroxide (hope not, I love BP!)
One should not use benzoyl peroxide on the same areas as hydroxyquinone. It would not be sensible, in any case. Both are irritating, and together one could expect relatively severe irritation.
>3. Any other safer/better way to fade acne scars?
Better, yes. Laser therapy. Bit more expensive, though. Hydroxyquinone is NOT permanent, and must be used to maintain the faded areas, which must be continually covered with sunscreens. Laser treatment has neither of these drawbacks, but might be a few more quid.
Pete Lassoff, Pharm.D. London
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Post by amylou on Feb 18, 2005 17:35:07 GMT -5
thanks nelly!! well let me tell u what...it sure does work
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Post by lauryn on Feb 21, 2005 16:29:59 GMT -5
im glad it works
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Post by lauryn on Mar 4, 2005 16:23:18 GMT -5
or it could be next on this list
Cosmetic Handbook
3. Cosmetic Product-Related Regulatory Requirements and Health Hazard Issues
Ingredient Labeling Cosmetics produced or distributed for retail sale to consumers for their personal care are required to bear an ingredient declaration (21 CFR 701.3). Cosmetics not customarily distributed for retail sale, e.g., hair preparations or make-up products used by professionals at their establishments and skin cleansing or emollient creams used at places of work, are exempt from this requirement provided these products are not also sold to consumers.
The ingredient declaration must be conspicuous so that it is likely to be read at the time of purchase. It may appear on any information panel of the package, i.e., the folding carton, box or wrapping if the immediate container is so packaged, and may also appear on a firmly affixed tag, tape or card. The letters must not be less than 1/16 of an inch in height (701.3(b)). If the total package surface available to bear labeling is less than 12 square inches, the letters must not be less than 1/32 of an inch in height (701.3(p)). Off-package ingredient labeling is permitted if the cosmetic is held in tightly compartmented trays or racks, it is not enclosed in a folding carton, and the package surface area is less than 12 square inches (701.3(i)).
The ingredients must be declared in descending order of predominance. Color additives (701.3(f)(3)) and ingredients present at one percent or less (701.3(f)(2)) may be declared without regard for predominance. The ingredients must be identified by the names established or adopted by regulation (701.3(c)); those accepted by the FDA as exempt from public disclosure may be stated as "and other ingredients" (701.3(a)).
Cosmetics which are also drugs must first identify the drug ingredient(s) as "active ingredient(s)" before listing the cosmetic ingredients (701.3(d)).
Prohibited Ingredients and other Hazardous Substances
Hexachlorophene (21 CFR 250.250). Because of its neurotoxic effect and ability to penetrate human skin, hexachlorophene (HCP) may be used only when an alternative preservative has not been shown to be as effective. The HCP concentration of the cosmetic may not exceed 0.1%, and it may not be used in cosmetics which in normal use may be applied to mucous membrane.
Mercury compounds (21 CFR 700.13). The use of mercury compounds as cosmetic ingredients is limited to eye area cosmetics at concentrations not exceeding 65 parts per million (0.0065%) of mercury calculated as the metal (about 100 ppm or 0.01% phenylmercuric acetate or nitrate) and provided no other effective and safe preservative is available for use.
Mercury compounds are readily absorbed through the skin on topical application and have the tendency to accumulate in the body. They may cause allergic reactions, skin irritation or neurotoxic manifestations.
Chlorofluorocarbon propellants (21 CFR 700.23 and 2.125). The use of chlorofluorocarbon propellants (fully halogenated chlorofluoroalkanes) in cosmetic aerosol products intended for domestic consumption is prohibited.
Chlorofluorocarbon-containing cosmetic aerosol products may continue to be manufactured for export provided they are not in conflict with the laws of the country to which they are to be exported and the following control system is being followed to ensure that there is no likelihood, by mistake or otherwise, of diversion of such products into domestic commerce:
(a) The manufacturer has an order from the foreign purchaser stating the exact amount desired, that a chlorofluorocarbon be used as propellant, and that he is aware of its illegality in the United States. The manufacturer must also have in his possession a current letter from a responsible official of the country to which the product is to be shipped stating that the use of chlorofluorocarbon propellants is legal in the respective country. (b) The stock of chlorofluorocarbon propellants intended for export production is kept under adequate security at all times.
(c) During all stages of manufacture and storage the chlorofluorocarbon-containing aerosol product is kept segregated from all other products and is clearly marked "for export only."
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Post by lauryn on Mar 4, 2005 16:23:39 GMT -5
(d) Complete records are kept accounting for all chlorofluorocarbon propellant use as well as for all manufacture, storage, shipment and exportation of aerosol products containing these propellants. These records must be retained for at least 3 years and made available to any FDA official upon oral or written request.
Other prohibited ingredients. The following additional substances are prohibited as cosmetic ingredients, (but not as unintentional contaminants of cosmetics manufactured in accordance with current good manufacturing practices):
(a) Bithionol because of its likelihood of causing photo-contact sensitization (21 CFR 700.11).
(b) Halogenated salicylanilides (di-, tri-, metabromsalan and tetrachlorosalicylanilide) because of their potential of causing photocontact sensitization (21 CFR 700.15).
(c) Chloroform because of its animal carcinogenicity and likely hazard to human health (21 CFR 700.18).
(d) Vinyl chloride as an ingredient of aerosol products because of its carcinogenic effect in humans and animals (21 CFR 700.14).
(e) Zirconium-containing complexes in aerosol cosmetic products because of their toxic effect on lungs, including granulomas (21 CFR 700.16).
(f) Methylene chloride because of its animal carcinogenicity and likely hazard to human health (21 CFR 700.18).
Acetylethyltetramethyltetralin (AETT). AETT should not be used in fragrance formulations and finished cosmetic products (usually in products claiming to be fragrance-free). In a subchronic toxicity study in rats conducted in 1977, AETT was found to cause serious neurotoxic disorders and discoloration of internal organs. It was also determined to penetrate human skin. The fragrance industry voluntarily discontinued use of AETT in 1978.
Musk ambrette. Various tests and clinical experience have demonstrated that musk ambrette may cause photocontact sensitization, i.e., allergic reactions of the skin on exposure to musk ambrette and sunlight. Other studies have indicated that musk ambrette may also cause neurotoxic effects. The International Fragrance Association has recommended that musk ambrette should not be used in products applied to the skin, particularly those products used on skin that is customarily also exposed to sunlight.
6-Methylcoumarin (6-MC). The fragrance ingredient 6-MC is a potent photo-contact sensitizer which may cause serious skin and systemic disorders in some consumers on contact in the presence of sunlight. Between 1976 and 1978, the FDA received many reports of adverse reactions associated with the use of 6-MC-containing suntan preparations. The photocontact allergenicity of 6-MC was subsequently confirmed in clinical studies. In 1978, the FDA asked the manufacturers of suntan and sunscreen products to discontinue the use of 6-MC. Two firms voluntarily recalled products containing 6-MC from the market.
Nitrosamines. Cosmetics containing as ingredients amines or amino derivatives, particularly di- or triethanolamine, may form nitrosamines if they also contain an ingredient which acts as a nitrosating agent as, for example, 2-bromo-2-nitropropane-1,3-diol (Bronopol, Onyxide 500), 5-bromo-5-nitro-1,3-dioxane (Bronidox C) or tris(hydroxymethyl)nitromethane (Tris Nitro), or if they are contaminated with a nitrosating agent, e.g., sodium nitrite. Amines and their derivatives are mostly present in creams, cream lotions, hair shampoos and cream hair conditioners. The nitrosation may occur during manufacture or during product storage.
Many nitrosamines have been determined to cause cancer in laboratory animals. They have also been shown to penetrate the skin. Nitrosamine contamination of cosmetics became an issue in early 1977. In a study of 29 cosmetic creams and lotions, N-Nitrosodiethanolamine (NDELA) was determined in 27. The levels of NDELA contamination ranged from less than 10 parts per billion (ppb) to 50 parts per million (ppm). Of the more than 300 cosmetic samples analyzed in 1978, 1979 and early 1980 in FDA's laboratories, 7% contained less than 30 ppb NDELA, 26% contained 30 ppb to 2 ppm and 7% contained between 2 ppm and 150 ppm.
The FDA expressed its concern about the contamination of cosmetics with nitrosamines in a notice published in the Federal Register of April 10, 1979 (44 FR 21365). It stated that cosmetics containing nitrosamines may be considered adulterated and subject to enforcement action. In surveys of cosmetic products conducted in 1991-92, NDELA was found in 65% of the samples at levels up to 3 ppm.
Dioxane. Cosmetics containing as ingredients ethoxylated surface active agents, i.e., detergents, foaming agents, emulsifiers and certain solvents identifiable by the prefix, word or syllable "PEG," "Polyethylene," "Polyethylene glycol," "Polyoxyethylene," "-eth-," or "-oxynol-," may be contaminated with 1,4-dioxane. It may be removed from ethoxylated compounds by means of vacuum stripping at the end of the polymerization process without an unreasonable increase in raw material cost.
In rodent feeding studies conducted for the National Cancer Institute, 1,4-dioxane was found to produce cancer of the liver and the nasal turbinates. It also caused systemic cancer in a skin painting study. Skin absorption studies demonstrated that dioxane readily penetrates animal and human skin from various types of vehicles. However, it was also determined that most of the dioxane applied to the skin in a vehicle evaporates into the environment and may not be available for skin absorption.
The contamination of ethoxylated surface-active agents with dioxane was first reported in 1978. Many of the raw materials analyzed since then have been found to contain dioxane; some contained as much as, or more than, 100 ppm. In finished cosmetic products containing ethoxylated surface-active agents, the incidence and level of dioxane contamination was significantly lower.
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Post by alex21 in cali on Mar 30, 2005 5:10:27 GMT -5
so if I get this stuff can I smear it all over the area speckled w/ dark spots or will it only work if I meticulously dot it on? I use self tanner any experience w/ the two? thanks I'm excited!
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